Antimicrobial and antioxidant activity of the polyphenol mangiferin

I. STOlLOVA, S. GARGOVA, A. STOYANOVA, L. HO

Abstract

The antimicrobial effect of the polyphenol mangiferin obtained from leaves of mango trees was studied according to the diffusion method. The solutions of mangiferin in polyethylene glycol-400 showed an activity with regard to seven bacterial and five fungal species - Bacillus pumilus, Bacillus cereus, Staphylococcus aureus, Staphylococcus citreus, Escherichia coli, Salmonella agona, Klebsiella pneumoniae, Saccharomyces cerevisiae, Thermoascus aurantiacus, Trichoderma reesei, Aspergillus flavus and Aspergillus fumigatus. Its antioxidant activity with regard to the free radical 2,2-diphenyl-l-picrylhydrazyl (DPPH) was also studied, as the concentration of mangiferin causing 50% inhibition of the free radical (IC50) was assayed to be 7.5 +/- 0.0075 mikrog/ml.
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