Tolerability and efficacy of Bioaron C® syrup in treatment of upper respiratory tract infections in children. Results of a post-marketing surveillance study in Poland

M. HOROSZKIEWICZ-HASSAN, N. BEUSCHER, R. LEHNFELD, U. THEISS, E. PFARR

Abstract

A post-marketing surveillance study (PMSS) was carried out in Poland with 313 children aged 3-10. predisposed to upper respiratory tract infections. The study participants received Bioaron C syrup, containing aqueous extract of Aloe arborescens leaves, juice of Aronia melanocarpa fruit and ascorbic acid. The main object of the present study was to investigate its tolerability and influence on the course of an acute URTI in children. Among the study participants 14% received Bioaron C as a single medication and 86% of the patients received concomitant medications. The efficacy of the treatment was measured according to a validated symptom score. The best results were obtained for symptoms related to rhinitis and bronchitis but there was no major effect seen on pain and fever. Within the subscores rhinitis and bronchitis Bioaron C alone was able to lead to an improvement and could contribute to a reduction in particular of the single symptoms blocked and runny nose, cough and hoarseness. Treatment with Bioaron C resulted in a significant improvement of the symptomology of URTI. Bioaron C was tolerated very well.
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