Chemical composition, antimicrobial and antioxidant activities of Dittrichia graveolens (L.) Greuter essential oil
Abstract
The aim of the study was to survey the chemical composition, antimicrobial and antioxidant
activities of Dittrichia graveolens essential oil in in vitro conditions. GC-FID and GC-MS
analyses were performed to evaluate the chemical composition of essential oil. The antimicrobial
activity against different kinds of microorganisms was determined by microbroth
dilution assay. The antioxidant activity was evaluated by DPPH free radical scavenging
system. Studies of chemical composition of essential oil revealed the presence of borneol
(38.2%) and bornyl acetate (14.9%) as major constituents. Essential oil showed strong antimicrobial
activity against Enterococcus faecalis isolates and Bacillus cereus. Staphylococcus
aureus and Escherichia coli are less sensitive to the oil. The strong antimicrobial activity
of oil against clinical isolates of bacteria was demonstrated. In addition, D. graveolens oil
notably reduced the concentration of DPPH free radical with higher efficacy than that of
trolox at 70 min.