Microbiological study of extracts of Salvia miltiorrhiza Bunge roots
Roots of Salvia miltiorrhiza Bunge contain mainly fractions of water-soluble substances. Most tanshinones are found in ethyloacetate fractions, slightly less in hexane extract. Tanshinones in water extracts have not been found. Ethyloacetate and hexane extracts from Salvia miltiorrhiza Bunge root are characterized by high microbiological activity (MIC range of 10–75 μg/ml using standard strain Staphylococcus aureus FDA 209P). The highest activity and maximum amount of cryptotanshinone was found in extracts obtained from roots of Polish origin. The microbiological activity of water fraction is quite low regardless of the source of raw material (MIC range 500-1000 μg/ml). The results suggest that the microbiological activity of Salvia miltiorrhiza Bunge extracts depends on the quality and quantity of tanshinones composition.